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Contact sensitivity to cigarettes and matches.

G Dawn1, C J Fleming, A Forsyth

  • 1Contact Dermatitis Investigation Unit, Glasgow Royal Infirmary, UK.

Contact Dermatitis
|May 27, 1999
PubMed
Summary

Patch testing identified cigarette and match components causing allergic reactions in patients with eczema. Stopping smoking improved eczema in most cases, suggesting these allergens are relevant for smokers.

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Area of Science:

  • Dermatology
  • Allergology
  • Toxicology

Background:

  • Cigarette smoking and match use are common activities.
  • Contact dermatitis is a prevalent skin condition.
  • Identifying specific allergens is crucial for effective management.

Purpose of the Study:

  • To evaluate the diagnostic utility of patch testing with cigarette and match components.
  • To identify common allergens in smokers presenting with eczema.
  • To assess the impact of smoking cessation on eczema severity.

Main Methods:

  • Retrospective review of patch test results from 1987 and 1997.
  • Analysis of reactions to a series including cigarette and match components.
  • Correlation of patch test results with clinical presentation and smoking habits.

Main Results:

  • 314 patients underwent patch testing; 31 (9.9%) showed relevant positive reactions.
  • Cigarette components caused relevant positive reactions in 26 patients.
  • Phosphorus sesquisulfide (a match component) was a significant allergen, particularly in 1987.

Conclusions:

  • Patch testing with cigarette and match components can identify relevant allergens in smokers with eczema.
  • A significant association exists between cigarette smoking and fragrance hypersensitivity.
  • Smoking cessation led to eczema improvement in a majority of affected patients.

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