Related Experiment Video
Updated: Aug 13, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 12, 2014
Recurrent pleomorphic adenoma of the head and neck
M Yasumoto1, K Sunaba, H Shibuya
1Department of Radiology, Tokyo Medical and Dental University, Japan. yasumoto.mrad@med.tmd.ac.jp
Abstract:
We reviewed the clinical and imaging files of 15 patients with pathologically confirmed recurrent pleomorphic adenomas of the head and neck. The primary tumours were in the lacrimal gland (1 case), cheek (2), palate (5), parotid gland (4), and submandibular gland (3). Recurrence was generally late, with an average of 14.9 years between initial surgery and recurrence. Multiple recurrent tumours, measuring 5-50 mm were found in eight patients. In all palatal cases recurrence was large and solitary. Most recurrent pleomorphic adenomas were well delineated with smooth margins, like most primary tumours. Irregularity of the margins was seen in four patients. In four of the five tumours of the palate and in the orbital lesion, the recurrent tumours caused bone destruction, thus mimicking malignant lesions. Irregular-margined recurrences seem to be rather small and found among multiple recurrent nodules.
Related Concept Videos
Abnormal Proliferation
Pharynx
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
Poliomyelitis
Cellular Adaptation IV: Dysplasia and Metaplasia
Esophageal Achalasia

