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Updated: Jul 30, 2026

Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

Assembly of functionally active Drosophila origin recognition complex from recombinant proteins.

I Chesnokov1, M Gossen, D Remus

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720 USA.

Genes & Development
|May 27, 1999
PubMed
Summary

Researchers identified unique genes for the origin recognition complex (ORC) in Drosophila. This suggests DNA replication origins aren't solely regulated by diverse ORC protein families, as the reconstituted complex restored replication in depleted extracts.

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