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A new antibiotic nortriterpene quinone methide from Maytenus catingarum
N L Alvarenga1, C A Velázquez, R Gómez
1Departamento de Fitoquímica, Dirección de Investigación, Facultad de Ciencias Químicas de la Universidad Nacional de Asunción, P.O. Box 1.055 Asunción, Paraguay. na-fcq@sce.cnc.una.py
Journal of Natural Products
|May 29, 1999
Abstract:
15alpha-Hydroxy-21-keto-pristimerine (1), a new nortriterpene quinone methide was isolated from the root bark of Maytenus catingarum along with other well-known related compounds, including pristimerine (2), tingenone, and 20alpha-hydroxy-tingenone. The structure of 1 was determined by means of 1H and 13C NMR spectroscopy, including homonuclear and heteronuclear correlations. Compound 1 showed antibiotic activity against Gram-positive bacteria.