Related Experiment Videos
Semisynthesis of 3-beta-hydroxyartemisinin
1Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Washington, DC 20307-5100, USA.
Journal of Natural Products
|May 29, 1999
Abstract:
3-beta-Hydroxyartemisinin (5) was synthesized from 3-beta-hydroxydihydroartemisinic acid (7c) via singlet oxygen oxidation followed by air (triplet oxygen) oxidation. Compound 7c was synthesized in two steps from dihydroartemisinic acid, 7a.