Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anesthesia for pediatric external beam radiation therapy.

J T Fortney1, E C Halperin, C M Hertz

  • 1Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA.

International Journal of Radiation Oncology, Biology, Physics
|May 29, 1999
PubMed
Summary

Pediatric anesthesia for external beam radiation therapy (EBRT) is frequently needed for children aged 3 years and younger. Sepsis occurred in 15% of patients with central venous access lines, especially those with prior chemotherapy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prospective study of neuropsychologic testing and quality-of-life assessment of adults with primary malignant brain tumors.

International journal of radiation oncology, biology, physics·2003
Same author

Should academic medical centers conduct clinical trials of the efficacy of intercessory prayer?

Academic medicine : journal of the Association of American Medical Colleges·2001
Same author

Anaesthetic considerations for a child with combined Prader-Willi syndrome and mitochondrial myopathy.

Paediatric anaesthesia·2001
Same author

The Jewish problem in U.S. medical education, 1920-1955.

Journal of the history of medicine and allied sciences·2001
Same author

Duration of symptoms prior to diagnosis is related inversely to presenting disease stage in children with medulloblastoma.

Cancer·2001
Same author

Non-human to human organ transplantation: its biologic basis and a potential role for radiation therapy.

International journal of cancer·2001

Area of Science:

  • Pediatric Anesthesiology
  • Radiation Oncology
  • Pediatric Oncology

Background:

  • Anesthesia is often necessary for radiotherapy in very young patients.
  • This can lead to multiple exposures to anesthetic agents within a short timeframe.
  • This study examines children undergoing external beam radiation therapy (EBRT).

Purpose of the Study:

  • To analyze the characteristics and outcomes of children requiring anesthesia for external beam radiation therapy (EBRT).
  • To determine the frequency of anesthesia use based on age and diagnosis.
  • To identify complications associated with anesthesia in this pediatric population.

Main Methods:

  • A consecutive series of 512 children aged 16 years or younger who received EBRT between 1983 and 1996 were reviewed.

Related Experiment Videos

  • Data collected included patient demographics, diagnosis, anesthesia techniques, monitoring, airway management, complications, and outcomes.
  • Specific focus was placed on patients requiring anesthesia.

    • Main Results:

    • 123 of 512 children (24%) required 141 anesthesia courses for EBRT, with the highest need in children aged 3 years or younger (96% for <=1 year, 93% for 1-2 years, 80% for 2-3 years).
    • Common diagnoses included primary CNS tumors (28%) and retinoblastoma (27%).
    • The mean number of anesthesia sessions was 22 per patient, with 15% of those with central venous lines developing sepsis, particularly those with prior chemotherapy (73%).

    Conclusions:

    • Anesthesia for EBRT is generally required for children aged 3 years or younger and rarely for those older than 5 years.
    • Sepsis was observed in 15% of patients utilizing central venous access lines.
    • Prior chemotherapy exposure was a significant factor in sepsis development among patients with central lines.