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Updated: Aug 4, 2026

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
Published on: January 27, 2023
Utility of cardiac catheterization in pediatric cardiac patients on ECMO
S E desJardins1, D C Crowley, R H Beekman
1Division of Pediatric Cardiology, C.S. Mott Children's Hospital, Ann Arbor, Michigan 48104-0204, USA.
Insights
Cardiac catheterization is feasible in children on extracorporeal membrane oxygenation (ECMO), offering valuable diagnostic and interventional benefits. However, long-term survival for these critically ill pediatric patients remains poor.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Critical Care Medicine
Background:
- Extracorporeal membrane oxygenation (ECMO) is a life-support measure for critically ill children with cardiac or respiratory failure.
- Cardiac catheterization is rarely performed in pediatric patients undergoing ECMO due to perceived risks.
- Congenital heart disease (CHD) is a common indication for ECMO in children.
Purpose of the Study:
- To evaluate the safety and efficacy of cardiac catheterization in pediatric patients on ECMO.
- To assess the diagnostic yield and impact on clinical management of catheterization in this population.
- To determine the outcomes and survival rates of children undergoing catheterization while on ECMO.
Main Methods:
- Retrospective review of 15 pediatric patients with CHD who underwent cardiac catheterization on ECMO between December 1990 and December 1995.
- Analysis of procedural success, diagnostic information obtained, changes in clinical management, complications, and survival rates.
- Inclusion of both diagnostic and interventional catheterization procedures.
Main Results:
- Catheterization procedures, including four interventions, were successful in all 15 patients.
- Unexpected diagnostic information was obtained in 40% of cases, significantly altering clinical management in 73%.
- All patients tolerated the procedure and transport well, with one instance of retroperitoneal hemorrhage. Survival rates were 50% weaning from ECMO, 29% at discharge, and 14% at follow-up.
Conclusions:
- Diagnostic and interventional cardiac catheterization can be performed safely in pediatric patients on ECMO, with acceptable morbidity and mortality.
- While catheterization provides valuable clinical information and management changes, the overall long-term survival for this high-risk pediatric population remains poor.
- Further research is needed to improve outcomes for children requiring both ECMO and cardiac catheterization.
Abstract:
Cardiac catheterization has been utilized rarely in children on extracorporeal membrane oxygenation (ECMO). We performed a retrospective review of 15 children with congenital heart disease who had undergone catheterization while on ECMO from December 1990-December 1995. The procedures, including four interventions, were successful in all patients with adequate evaluation of clinical questions. Unexpected diagnostic information of clinical importance was obtained in 40%, and clinical management of patients was significantly altered in 73%. All patients tolerated the procedure and transport well. The only significant complication was a retroperitoneal hemorrhage in one patient after approximately 12 hr. Although no patients died at catheterization, overall survival was poor, with 50% weaning from ECMO, 29% surviving to discharge, and 14% surviving at follow-up. We conclude that diagnostic and interventional catheterization may be performed in patients on ECMO with acceptable morbidity and mortality; however, long-term survival in this population is poor.
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