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[Leukemic neutrophilic dermatosis].

L Török1, A Kirschner, M Gurzó

  • 1Bács-Kiskun megyei Onkormányzat Kórház Börgyógyászata, Kecskemét.

Orvosi Hetilap
|June 1, 1999
PubMed
Summary

A rare case of acute myeloid leukemia manifested initially as Sweet's syndrome and gangrenous pyoderma, a condition termed "leukemic neutrophilic dermatosis". This dermatosis holds significant diagnostic and prognostic value for leukemia.

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Area of Science:

  • Dermatology
  • Hematology
  • Oncology

Background:

  • Acute myeloid leukemia (AML) can present with unusual dermatological manifestations.
  • Sweet's syndrome and pyoderma gangrenosum are inflammatory skin conditions that can be associated with hematological malignancies.

Observation:

  • A 67-year-old female patient with acute myeloid leukemia presented with Sweet's syndrome as the initial symptom.
  • Subsequently, the patient developed signs of gangrenous pyoderma.

Findings:

  • The combined presentation of Sweet's syndrome and gangrenous pyoderma in this context is termed "leukemic neutrophilic dermatosis" (LND).
  • This transient LND form was the first manifestation of the underlying acute myeloid leukemia.

Implications:

  • Leukemic neutrophilic dermatosis has significant diagnostic value, potentially indicating an underlying hematological malignancy.
  • Recognizing LND is crucial for early diagnosis and can have prognostic implications in patients with acute myeloid leukemia.

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