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[Chronic urticaria. Provocation test].

J M Giménez Camarasa

    Medicina Cutanea Ibero-Latino-Americana
    |January 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    The provocation test identified food inducers in 33.3% of chronic urticaria patients. Tartrazine was a common trigger, particularly in those sensitive to aspirin, suggesting its use in detecting aspirin sensitivity.

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    Area of Science:

    • Clinical immunology and allergy
    • Dermatology

    Context:

    • Chronic urticaria affects a significant patient population with diverse triggers.
    • Identifying specific inducers is crucial for effective management and treatment of chronic urticaria.

    Purpose:

    • To evaluate the efficacy of the provocation test in identifying specific food and chemical inducers of chronic urticaria.
    • To investigate the association between tartrazine sensitivity and aspirin sensitivity in patients with chronic urticaria.

    Summary:

    • A provocation test was administered to sixty chronic urticaria patients (ages 11-64).
    • Responses were observed in 33.3% of patients, with tartrazine identified as the most frequent inducer.
    • Tartrazine sensitivity was notably linked to aspirin sensitivity, even without direct aspirin provocation, suggesting tartrazine as a potential surrogate marker.

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    Impact:

    • The provocation test is a valuable tool for diagnosing chronic urticaria of unknown etiology.
    • Findings highlight the importance of dietary elimination of identified triggers, such as tartrazine, for symptom management.
    • This study provides evidence for using tartrazine provocation to infer aspirin sensitivity in certain urticaria patients.