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Families of arsenic transporters
1Dept of Biochemistry and Molecular Biology, Wayne State University, School of Medicine, Detroit, MI 48201, USA. brosen@med.wayne.edu
Trends in Microbiology
|June 4, 1999
Abstract:
Bacterial arsenic resistance (ars) operons encode an arsenite-efflux system that can be a secondary carrier protein (ArsB) or an anion-translocating ATPase (ArsAB). Yeasts extrude arsenite using Acr3p, a plasma membrane carrier protein, or sequester it in vacuoles as the glutathione conjugate using Ycf1p, an ABC transporter.