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Related Experiment Videos

[Three-dimensional breast biopsy and surgery].

K J Winzer1, S Filimonow, H D Frohberg

  • 1Klinik für Allgemein-, Viszeral-, Gefäss- und Thoraxchirurgie, Universitätsklinikum Charité der Humboldt-Universität zu Berlin.

Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen
|June 4, 1999
PubMed
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The ABBI system offers optimal three-dimensional breast biopsy for non-palpable tumors, improving localization accuracy. While digital mammography excels at microcalcification detection, sonography is recommended for other suspicious findings.

Area of Science:

  • Oncology
  • Radiology
  • Surgical Pathology

Background:

  • Accurate histological verification of non-palpable breast tumors is crucial for diagnosis and treatment planning.
  • Conventional biopsy methods can face challenges with localization and complete tumor removal.
  • The ABBI (Advanced Breast Biopsy Instrumentation) system offers a novel approach to breast lesion extirpation.

Purpose of the Study:

  • To evaluate the efficacy of the ABBI system for three-dimensional breast biopsy in diagnosing suspicious non-palpable breast tumors.
  • To compare the sensitivity of digital mammography integrated with the ABBI system versus conventional mammography for detecting radiomorphological signs.
  • To assess the rate of residual tumor and the suitability of the ABBI cylinder for breast-conserving lumpectomy.

Main Methods:

Related Experiment Videos

  • Cylindrical extirpation using the ABBI system for histological verification of suspicious non-palpable breast tumors.
  • Intraoperative digital mammography for localization verification and assessment of microcalcification removal.
  • Preoperative sonography for marking focal shadows and structural irregularities not optimally detected by digital mammography.
  • Histopathological analysis of excised specimens to determine tumor type, extent, and margin status (R1 resection).

Main Results:

  • The ABBI system facilitated accurate localization and extirpation in 80 cases, identifying 13 invasive and 8 intraductal carcinomas.
  • Digital mammography within the ABBI system showed higher sensitivity for microcalcifications but lower sensitivity for focal shadows and structural irregularities compared to conventional methods.
  • In 7 procedures to exclude recurrence, 3 intraductal and 1 invasive carcinoma were detected.
  • Breast-conserving therapy was indicated in 8 of 12 invasive and 1 of 5 intraductal carcinomas.
  • Two invasive carcinomas were suitable for lumpectomy using the ABBI cylinder without a second excision due to clear margins (>2 mm) and no extensive intraductal component.

Conclusions:

  • The ABBI system is an effective tool for the histological verification of suspicious non-palpable breast tumors, enabling precise extirpation.
  • Integrated digital mammography aids in intraoperative localization and microcalcification assessment, though sonography is recommended for other findings.
  • The ABBI system shows potential for breast-conserving lumpectomy in select cases, reducing the need for re-excision.