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Updated: Aug 13, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Individualized surgical strategy for the reduction of stroke risk in patients undergoing coronary artery bypass
M Gaudino1, F Glieca, F Alessandrini
1Department of Cardiac Surgery, Catholic University, Rome, Italy. mgaudino@pelagus.it
Insights
Systematic screening and tailored surgical strategies for the ascending aorta and carotid arteries effectively reduce stroke risk in coronary artery bypass grafting patients. However, this approach may increase angina recurrence in high-risk individuals.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Vascular Medicine
Background:
- Coronary artery bypass grafting (CABG) carries a risk of perioperative stroke.
- Systematic screening of the ascending aorta and internal carotid arteries can identify patients at higher neurologic risk.
- Individualizing surgical strategy based on vascular status is crucial for patient outcomes.
Purpose of the Study:
- To evaluate a protocol for systematic screening of the ascending aorta and internal carotid arteries.
- To assess the efficacy of individualized surgical strategies in reducing stroke incidence during CABG.
- To determine the impact of risk stratification on perioperative stroke rates.
Main Methods:
- A cohort of 2,326 patients undergoing CABG were screened pre- and intraoperatively.
- Patients were categorized into low, moderate, and high neurologic risk groups based on screening results.
- High-risk patients received dedicated surgical techniques, prioritizing neurologic risk reduction over complete revascularization.
Main Results:
- The incidence of perioperative stroke was similar across all risk groups (1.1-1.3%).
- No significant difference in stroke rates was observed between high-risk and other groups.
- Angina recurrence was significantly higher in the high-risk group compared to lower-risk groups.
Conclusions:
- The implemented screening and individualized surgical strategy effectively achieved a low perioperative stroke rate in high-risk CABG patients.
- The trade-off between reduced neurologic risk and potential for increased angina recurrence requires further investigation.
- This strategy demonstrates a potential benefit for managing neurologic complications in complex cardiac surgery.
Background:
This study was designed to evaluate the efficacy of a protocol of systematic screening of the ascending aorta and internal carotid arteries and individualization of the surgical strategy to the ascending aorta and internal carotid arteries status in reducing the stroke incidence among patients undergoing coronary artery bypass grafting.
Methods:
On the basis of a pre- and intraoperative screening of the ascending aorta and internal carotid arteries, 2,326 consecutive patients undergoing coronary artery bypass grafting were divided in low, moderate, and high neurologic risk groups. In the high-risk group dedicated surgical techniques were always adopted and the reduction of the neurologic risk was considered more important than the achievement of total revascularization.
Results:
The incidence of perioperative stroke in the high-risk group was similar to those of the other two groups (1.1 versus 1.3 and 1.1%, respectively; p = not significant); however, angina recurrence was significantly more frequent in the high-risk group.
Conclusions:
The described strategy allows a low rate of perioperative stroke in high-risk patients undergoing coronary artery bypass grafting. Whether the reduction of the neurologic risk outweighs the benefits of complete revascularization remains to be determined.
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