Related Experiment Video
Updated: Jan 4, 2026

08:26
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
1.3K
Total pelvic exenteration for advanced rectal cancer
1Department of Surgery, USD School of Medicine, Sioux Falls, SD, USA.
Summary
Recurrent colorectal cancer, especially in the pelvis, is challenging but manageable. This review highlights diagnostic and therapeutic strategies for locally recurrent colorectal cancer, offering survival and palliative benefits.
Area of Science:
- Oncology
- Surgical Oncology
- Gastroenterology
Background:
- Colorectal cancer recurrence rates range from 25% to 50% after curative resection.
- Locoregional recurrence occurs in up to 19% of colon and 33% of rectal cancers.
- Pelvic recurrences are often deemed unsalvageable, unlike hepatic or pulmonary metastases.
Purpose of the Study:
- To review diagnostic and therapeutic strategies for locally recurrent colorectal cancer.
- To emphasize the potential for survival or palliative benefits in select patients.
- To address the challenges and traditional under-treatment of pelvic recurrences.
Main Methods:
- Literature review of diagnostic modalities for locally recurrent colorectal cancer.
- Analysis of surgical and non-surgical therapeutic options.
- Evaluation of outcomes for different management strategies.
Main Results:
- Locoregional recurrence is a significant clinical challenge.
- Aggressive intervention for pelvic recurrence can offer survival benefits.
- Careful patient selection is crucial for successful outcomes.
Conclusions:
- Locally recurrent colorectal cancer requires tailored diagnostic and therapeutic approaches.
- Surgical resection, despite technical demands, can be valuable.
- A multidisciplinary approach is essential for optimizing patient management and outcomes.

