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Updated: Oct 20, 2026

Isolation and Identification of Extravascular Immune Cells of the Heart
Published on: August 23, 2018
[Infectious endocarditis: immune disorders, differentiated therapy]
Aim:
Immunological assessment of variants of infectious endocarditis (IE) and design of differentiated approach to the disease therapy.
Materials And Methods:
Of 150 patients treated (90 males and 60 females, mean age 41.9 +/- 3.3 years) 28.7% and 71.3% had primary and secondary endocarditis, respectively. With chronization of the process, there was a trend to growing immune unbalance (IU).
Results:
The IU in IE patients manifested with leukocytosis changing for leukopenia, reduced absolute and relative number of lymphocytes, complement, T- and B-lymphocytes, growing content of CIC, IgM, rheumatoid factor and cryoproteins.
Conclusion:
Besides antibacterial therapy, IE patients need immunocorrective and efferent therapy.
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