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Intracellular signaling: Fleshing out the TGFbeta pathway
1Waksman Institute, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854-8020, USA. padgett@waksman.rutgers.edu
Current Biology : CB
|June 9, 1999
Abstract:
Recent studies of the intracellular signaling pathway initiated by ligands of the transforming growth factor beta (TGFbeta) family have provided new insights into how the receptors for such ligands phosphorylate their substrates - the Smads - and how signaling specificity is achieved.