Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Comorbidity of STDs.

Purcell1, Chacko

  • 1UTMB MCH Clinic, 2530 S. Main, Stafford, TX 77477, USA.

Adolescent Medicine (Philadelphia, Pa.)
|October 1, 1996
PubMed
Summary

A young woman presented with severe symptoms, later diagnosed with multiple sexually transmitted infections including syphilis, herpes simplex virus type II, and HIV. These infections, along with Histoplasma capsulatum, were linked to a single sexual encounter.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vaginal douching in adolescents attending a family planning clinic

Journal of pediatric and adolescent gynecology·2000
Same author

Symptoms are a poor indication of severity of reflux in Barrett's oesophagus

The British journal of surgery·2000
Same author

ReplyellipsisThe sugar sensing story.

Trends in plant science·1999
Same author

Is hexokinase really a sugar sensor in plants?

Trends in plant science·1999
Same author

Severe Menorrhagia.

Adolescent medicine (Philadelphia, Pa.)·1996
Same author

Proton scattering by 206,207,208Pb at 650 MeV: Phenomenological analysis.

Physical review. C, Nuclear physics·1995

Area of Science:

  • Infectious Diseases
  • Immunology
  • Public Health

Background:

  • Adolescent health presents unique challenges in diagnosing complex infections.
  • Co-infections with sexually transmitted infections (STIs) can complicate clinical presentations.
  • Opportunistic infections in immunocompromised individuals require prompt identification.

Purpose of the Study:

  • To report a rare case of concurrent syphilis, herpes simplex virus type II, and HIV infection in an adolescent.
  • To highlight the diagnostic challenges and clinical manifestations of multiple STIs.
  • To emphasize the importance of comprehensive STI screening in at-risk populations.

Main Methods:

  • Case report of a 16-year-old female with a complex medical history.
  • Diagnostic workup included physical examination, imaging (chest x-ray), and extensive laboratory testing.
  • Cultures (herpes simplex, Histoplasma capsulatum), serological tests (syphilis, HIV), and molecular assays were performed.

Main Results:

  • The patient presented with fever, night sweats, abdominal pain, headache, rash, weight loss, and perineal ulcers.
  • Laboratory results confirmed active syphilis (positive RPR and MHA-TP), herpes simplex virus type II (positive genital ulcer culture), and HIV infection (positive ELISA and Western blot).
  • Chest x-ray revealed interstitial nodular densities, and lung biopsy was positive for Histoplasma capsulatum.

Conclusions:

  • A single sexual encounter led to the transmission of syphilis, herpes simplex type II, and HIV in this adolescent.
  • Concurrent infections with multiple STIs and opportunistic infections pose significant diagnostic and management challenges.
  • Comprehensive sexual health education and screening are crucial for adolescent populations.

Related Experiment Videos