Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Severe Menorrhagia.

Purcell1, Hergenroeder

  • 1UTMB MCH Clinic, 2503 S. Main, Stafford, TX 77477, USA.

Adolescent Medicine (Philadelphia, Pa.)
|October 1, 1996
PubMed
Summary

A teenage girl experienced prolonged menstrual bleeding and fatigue due to severe iron deficiency anemia and low platelet count. Treatment involved platelet transfusions and hormonal therapy, successfully normalizing her platelet levels.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Symptoms are a poor indication of severity of reflux in Barrett's oesophagus

The British journal of surgery·2000
Same author

ReplyellipsisThe sugar sensing story.

Trends in plant science·1999
Same author

Is hexokinase really a sugar sensor in plants?

Trends in plant science·1999
Same author

Comorbidity of STDs.

Adolescent medicine (Philadelphia, Pa.)·1996
Same author

Proton scattering by 206,207,208Pb at 650 MeV: Phenomenological analysis.

Physical review. C, Nuclear physics·1995
Same author

Pion elastic scattering from polarized 13C in the energy region of the P33 resonance.

Physical review. C, Nuclear physics·1994

Area of Science:

  • Hematology
  • Gynecology
  • Pediatric Medicine

Background:

  • Prolonged menstrual bleeding is a common gynecological issue in adolescents.
  • Severe iron deficiency anemia can present with systemic symptoms like fatigue and dizziness.
  • Bleeding disorders and associated thrombocytosis require careful diagnostic evaluation.

Purpose of the Study:

  • To present a case of prolonged menstrual bleeding in an adolescent.
  • To highlight the diagnostic challenges and management of reactive thrombocytosis secondary to iron deficiency anemia.
  • To discuss the therapeutic approach combining platelet support and hormonal therapy.

Main Methods:

  • Case report of a 15-year-old female with severe menorrhagia.
  • Laboratory investigations including complete blood count, platelet aggregometry, and antiplatelet antibody testing.
  • Treatment with platelet transfusion, ethinyl estradiol plus norethindrone therapy.

Main Results:

  • The patient presented with severe anemia and thrombocytopenia (platelet count 60,000-80,000/µL) with positive antiplatelet antibodies.
  • Diagnosis of reactive thrombocytosis secondary to severe iron deficiency anemia was established.
  • Treatment led to a significant increase in platelet count to 2,275,000/µL and stabilization.

Conclusions:

  • Severe iron deficiency anemia can precipitate complex hematological conditions like reactive thrombocytosis in adolescents.
  • A multidisciplinary approach involving hematology and gynecology is crucial for managing such cases.
  • Hormonal therapy combined with supportive care can effectively manage menorrhagia and associated hematological abnormalities.

Related Experiment Videos