Related Experiment Videos
Multistranded DNA structures
1Department of Chemistry and Biochemistry, University of California, Los Angeles 90095-1569, USA.
Current Opinion in Structural Biology
|June 11, 1999
Abstract:
DNA oligonucleotides can form multistranded helices through either the folding of a single strand or the association of two, three or four strands of DNA. Structures of several new DNA triplexes, G-quartet DNA quadruplexes and I-motif DNA quadruplexes have been reported recently. These structures provide new insights into helix stability and folding, loop conformations and cation interactions.