[Study by S-100 polyclonal antibodies of Langerhans cells in vocal cord polyps]

In 10 patients (5 smokers) with benign laryngeal polyp of a single vocal cord, a biopsy was performed. Five normal control specimens were obtained from the larynx of recently deceased patients who underwent postmortem study. Langerhans cells were counted in specimens of histologically normal and pathological vocal cord mucosa after identification with S-100 polyclonal antibody. Langerhans cells were 11.5-fold more common in the epithelium of vocal cord polyps than in the mucosa of normal vocal cords.