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[The relationship between coagulation time and bilateral occurrence in chronic subdural hematoma]
No to Shinkei = Brain and Nerve
|June 11, 1999
Summary
Bilateral chronic subdural hematomas are more common in patients with prolonged coagulation times, particularly in non-traumatic cases. This suggests impaired coagulation and platelet function contribute to the development of these hematomas.
Area of Science:
- Neurology
- Hematology
Context:
- Chronic subdural hematoma (CSH) is a significant clinical concern.
- Understanding risk factors for bilateral CSH is crucial for patient management.
Purpose:
- To investigate the association between coagulation status and the occurrence of bilateral chronic subdural hematomas.
- To analyze the role of prolonged prothrombin time (PT) and activated partial thromboplastin time (aPTT) in bilateral CSH.
Summary:
- A study of 137 CSH cases found bilateral hematomas were more frequent in patients with prolonged coagulation times (elevated PT and aPTT).
- This association was significant in non-traumatic cases, with higher prevalence in PT- and aPTT-elongated groups.
- Bilateral CSH also showed a tendency in patients undergoing hemodialysis or taking warfarin or anti-platelet drugs, indicating suppressed coagulation and platelet function involvement.
Impact:
- Findings suggest that impaired coagulation and platelet function are key factors in the pathogenesis of bilateral CSH.
- Highlights the importance of assessing coagulation status in patients with CSH, especially for those with bilateral presentation or on specific medications.