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Acute eosinophilic interstitial nephritis and uveitis (TINU syndrome) associated with granulomatous hepatitis
A Segev1, S Ben-Chitrit, Y Orion
1Department of Internal Medicine, Meir General Hospital, Kfar-Sava, Israel.
Clinical Nephrology
|June 11, 1999
Abstract:
A 23-year-old male presented with renal failure, cholestatic liver enzyme elevation and uveitis. Percutaneous renal biopsy revealed marked eosinophilic infiltration of the renal interstitium, which made the diagnosis of TINU syndrome (Tubulo-Interstitial Nephritis and Uveitis). Percutaneous liver biopsy showed granulomatous hepatitis, which was not described as a part of TINU syndrome. The diagnostic dilemma and the literature are discussed.