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Gln --> Arg 191 polymorphism of paraoxonase and Parkinson's disease
S Akhmedova1, S Anisimov, A Yakimovsky
1Laboratory of Human Molecular Genetics, St. Petersburg Nuclear Physics Institute, Russian Academy of Science, Russia.
Human Heredity
|June 12, 1999
Abstract:
We investigated the Gln --> Arg 191 polymorphism in paraoxonase (PON1) in St. Petersburg population, in three clinically differentiated groups of patients with Parkinson's disease (PD) and in the symptomatic tremor group. A new approach for Gln --> Arg 191 PON1 polymorphism genotyping is suggested. No significant differences in the groups studies as compared to the controls was observed.