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Atrial septal defect in Malta.

V Grech1

  • 1Paediatric Department, St. Luke's Hospital, Guardamangia, Malta. vgrech@mail.link.net.mt

Journal of Paediatrics and Child Health
|June 12, 1999
PubMed
Summary

This study on atrial septal defect (ASD) found diagnosis and surgical trends improved significantly. Early, noninvasive diagnosis and reduced mortality highlight ASD

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Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • Atrial septal defect (ASD) is a common congenital heart malformation.
  • Understanding diagnostic and surgical trends is crucial for patient management.
  • Population-based data provides insights into disease prevalence and natural history.

Purpose of the Study:

  • To analyze diagnostic and surgical trends for atrial septal defect (ASD).
  • To estimate the birth prevalence of ASD.
  • To determine spontaneous closure rates of ASD.

Main Methods:

  • Population-based cohort study in Malta (1990-1994).
  • Identification of all diagnosed ASD cases born within the study period.
  • Echocardiographic follow-up for non-intervention cases.

Main Results:

  • 190 ASD cases identified; significant decrease in age at diagnosis and surgery.
  • Shift towards entirely noninvasive diagnostic methods.
  • Dramatic reduction in perioperative mortality over time.
  • Birth incidence: 2.0/1000 live births (non-intervention) and 0.4/1000 (intervention).
  • 92% of non-intervention ASDs closed spontaneously; others decreased in size.

Conclusions:

  • Atrial septal defect (ASD) is generally a benign condition.
  • Early and noninvasive diagnosis is achievable.
  • Interventional mortality for ASD is extremely low.

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