Related Experiment Videos
ABR differences before and after dialyses
G Niedzielska1, E Katska, P Sikora
1Department of Paediatric Otorhinolaryngology, Phoniatry and Audiology, Medical University, Lublin, Poland.
Insights
This study evaluated hearing in children with end-stage renal failure undergoing hemodialysis. Brainstem auditory evoked response (ABR) changes suggest a link between uremia
Area of Science:
- Pediatric Nephrology
- Audiology
- Neurophysiology
Background:
- End-stage renal failure (ESRD) affects multiple organ systems.
- Children with ESRD often undergo regular hemodialysis.
- Potential impacts of ESRD and hemodialysis on auditory function are not fully understood.
Purpose of the Study:
- To objectively evaluate the hearing organ in children with ESRD.
- To investigate changes in auditory brainstem responses (ABR) related to hemodialysis.
- To explore the connection between ABR alterations and biochemical parameters of uremia.
Main Methods:
- Study included seven children (aged 6-17) with ESRD undergoing hemodialysis.
- Pure-tone audiometry was performed.
- Auditory brainstem responses (ABR), including latency and interpeak latency, were measured before and after hemodialysis sessions.
- Biochemical parameters of uremia were analyzed.
Main Results:
- Pure-tone audiometry results were normal in five out of seven children.
- Analysis of ABR revealed differences before and after hemodialysis.
- These ABR variations were found to be associated with specific biochemical markers of uremia.
Conclusions:
- Hemodialysis may induce transient changes in auditory pathway function in children with ESRD.
- ABR is a sensitive tool for detecting subclinical auditory alterations in this population.
- Further research is warranted to elucidate the long-term effects and underlying mechanisms.
Abstract:
The aim of the study was the objective evaluation of the hearing organ in children. Seven children aged 6-17 with end stage renal failure treated by haemodialysis were examined. Four- to five-hour dialyses were performed 2-3 times a week. Pure-tone audiometry was normal in five children. The reactions of brain stem responses (latency and interpeak latency) were analysed before and after haemodialyses. We conclude that the ABR differences were connected with biochemical parameters of uraemia. The present study is a preliminary one and will be continued in the future.