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Related Experiment Videos

ABR differences before and after dialyses.

G Niedzielska1, E Katska, P Sikora

  • 1Department of Paediatric Otorhinolaryngology, Phoniatry and Audiology, Medical University, Lublin, Poland.

International Journal of Pediatric Otorhinolaryngology
|June 12, 1999
PubMed
Summary

This study evaluated hearing in children with end-stage renal failure undergoing hemodialysis. Brainstem auditory evoked response (ABR) changes suggest a link between uremia

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Area of Science:

  • Pediatric Nephrology
  • Audiology
  • Neurophysiology

Background:

  • End-stage renal failure (ESRD) affects multiple organ systems.
  • Children with ESRD often undergo regular hemodialysis.
  • Potential impacts of ESRD and hemodialysis on auditory function are not fully understood.

Purpose of the Study:

  • To objectively evaluate the hearing organ in children with ESRD.
  • To investigate changes in auditory brainstem responses (ABR) related to hemodialysis.
  • To explore the connection between ABR alterations and biochemical parameters of uremia.

Main Methods:

  • Study included seven children (aged 6-17) with ESRD undergoing hemodialysis.
  • Pure-tone audiometry was performed.
  • Auditory brainstem responses (ABR), including latency and interpeak latency, were measured before and after hemodialysis sessions.

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  • Biochemical parameters of uremia were analyzed.

    • Main Results:

    • Pure-tone audiometry results were normal in five out of seven children.
    • Analysis of ABR revealed differences before and after hemodialysis.
    • These ABR variations were found to be associated with specific biochemical markers of uremia.

    Conclusions:

    • Hemodialysis may induce transient changes in auditory pathway function in children with ESRD.
    • ABR is a sensitive tool for detecting subclinical auditory alterations in this population.
    • Further research is warranted to elucidate the long-term effects and underlying mechanisms.