Low-frequency damped electroretinographic wavelets in young asymptomatic patients with dominant retinitis pigmentosa: a new electroretinographic finding
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Updated: Sep 22, 2026
Multifocal Electroretinograms
Published on: December 4, 2011
1Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida, USA.
Objective:
To describe a previously unreported electroretinographic (ERG) pattern in early retinitis pigmentosa (RP).
Design:
Two case reports.
Participants:
Two unrelated young asymptomatic patients with autosomal-dominant retinitis pigmentosa were studied.
Main Outcome Measures:
Clinical findings and ERG responses were assessed.
Results:
No ERG responses were detected scotopically with low-luminance stimuli. With increasingly brighter stimuli, a series of three to five low-frequency damped wavelets developed under both scotopic and photopic conditions. The period of the wavelets was 25 to 37 msec.
Conclusions:
Low-frequency damped ERG wavelets occur in some young asymptomatic patients with autosomal-dominant RP. The ERG pattern suggests that these wavelets are predominantly cone-generated.
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