Neuropathologic aspects of psychosis in children

On the basis of a search of the literature and extensive inquiries to clinicians, this paper catalogues those cases that contain any information concerning possible neuropathologic changes in cases of childhood autism or psychosis. In all, 33 cases were identified. Twenty-nine cases are from the literature; six of these are sibling pairs. Four cases were folnd by inquiry and have not been reported heretofore. Because of limitations in both the clinical and neuropathologic data in most of the case reports, the paper serves primarily as a source of reference to the 33 cases identified. The information that is available is presented along with some tentative suggestions for further research.