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Propranolol effectively treated polymyoclonia and opsoclonus in two infants. The medication significantly improved abnormal movements without causing adverse side effects.
Area of Science:
- Pediatric Neurology
- Clinical Pharmacology
Background:
- Polymyoclonia and opsoclonus are rare, severe involuntary movement disorders.
- Current treatment options for these conditions in infants are limited.
Abstract:
Two infants with the classical involuntary movements of polymyoclonia and opsoclonus were treated with propanolol in a dosage of 2 mg/kg/24 hr. There was a marked improvement in the abnormal movements in both children. No side effects of treatment were encountered.