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Mal de debarquement.

T C Hain1, P A Hanna, M A Rheinberger

  • 1Department of Neurology, Northwestern University Medical School, Chicago, Ill 60611, USA. thain@casbah.acns.nwu.edu

Archives of Otolaryngology--Head & Neck Surgery
|June 15, 1999
PubMed
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Mal de debarquement syndrome, often affecting middle-aged women after cruises, presents persistent symptoms. Treatments like benzodiazepines show more promise than vestibular suppressants or physical therapy for this condition.

Area of Science:

  • Neurology
  • Otolaryngology
  • Vestibular Disorders

Background:

  • Mal de debarquement syndrome (MdDS) is a condition characterized by a sensation of motion after cessation of motion.
  • Previous research has identified limited cases, necessitating further investigation into its clinical features and prevalence.

Purpose of the Study:

  • To describe the clinical characteristics of mal de debarquement syndrome.
  • To identify demographic patterns and symptom duration in MdDS patients.
  • To evaluate the efficacy of various treatment modalities for MdDS.

Main Methods:

  • A retrospective analysis of patients diagnosed with mal de debarquement syndrome.
  • Collection of data on patient demographics, symptom onset, duration, and constancy.

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  • Review of treatment responses to medications (meclizine hydrochloride, transdermal scopolamine, benzodiazepines) and physical therapy.

    • Main Results:

    • The study identified a significant number of MdDS cases, more than double previous reports.
    • The typical patient profile is a middle-aged woman, often experiencing symptoms after an ocean cruise.
    • Symptoms were constant in 85% of patients, with limited reported benefit from meclizine, scopolamine, or physical therapy; benzodiazepines showed the most benefit.

    Conclusions:

    • Mal de debarquement syndrome is more prevalent than previously thought, particularly in middle-aged women post-cruise.
    • MdDS symptoms are frequently persistent and often resistant to standard vestibular suppressant medications.
    • Further research is needed to understand the underlying mechanisms and develop more effective treatments for MdDS.