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Respiratory energetics during exercise at high altitude.

F Cibella1, G Cuttitta, S Romano

  • 1Istituto di Fisiopatologia Respiratoria del Consiglio Nazionale delle Ricerche, Palermo 90146, Italy 20100, USA. CIBELLA@IFRPA.IFR.PA.CNR.IT

Journal of Applied Physiology (Bethesda, Md. : 1985)
|June 16, 1999
PubMed
Summary

High altitude (HA) increases the work of breathing (Wrs) and maximal exercise ventilation (VEmax), potentially limiting external work capacity. This effect is more pronounced at higher mechanical efficiencies.

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Area of Science:

  • Physiology
  • Altitude Medicine
  • Exercise Science

Background:

  • High altitude environments pose physiological challenges.
  • Understanding the impact on respiratory mechanics is crucial for athletes and military personnel.

Purpose of the Study:

  • To evaluate the effects of high altitude (HA) on the work of breathing (Wrs) and external work capacity.
  • To compare respiratory parameters at sea level (SL) and after acclimatization to HA.

Main Methods:

  • Measured mechanical power of breathing (Wrs) using esophageal pressure and lung volume.
  • Assessed subjects during maximal exercise at SL and after a 1-month sojourn at 5,050 m.

Main Results:

  • Maximal exercise ventilation (VEmax) and maximal Wrs were significantly higher at HA compared to SL.

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  • Maximal O2 uptake was lower at HA.
  • The O2 cost of breathing at HA could substantially limit external work capacity, especially at lower mechanical efficiencies.

    • Conclusions:

    • High altitude significantly increases the work of breathing and may limit external work capacity.
    • The critical ventilation threshold for body energetics is exceeded at HA, even with higher mechanical efficiencies.