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Updated: Aug 18, 2026

DNA-affinity-purified Chip (DAP-chip) Method to Determine Gene Targets for Bacterial Two component Regulatory Systems
Published on: July 21, 2014
[Analysis of an operator-like structure, regulating the activity of the ribC gene in Bacillus subtilis]
R A Kreneva1, B M Polanuer, I M Solov'eva
1Department of Molecular and Radiation Biophysics, Konstantinov Institute of Nuclear Physics, Russian Academy of Sciences, Gatchina, St. Petersburg, Russia.
Abstract:
A point mutation (C-->A substitution) in the -35 region of a putative promoter-operator site TTGCCG-17n-TACATT results in a more than 25-fold increase in the activity of ribC gene encoding the bifunctional enzyme--flavokinase/FAD-synthase--in Bacillus subtilis.
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