[Microbiological synthesis of virazole by immobilized cells]

Based on the isotherms of adsorption of the cells of Xanthomonas campestris B-610 to glass and polyvinyl fibers, immobilized systems were produced, in which the cell content was sufficient for enzymatic synthesis of Virazole (1-[beta-D-ribofuranosyl]-1,2,4-triazole-3-carboxamide) using adenosine as a donor of ribose (50-60% conversion of 1,2,4-triazole-3-carboxamide). The immobilized cells thus obtained retain their enzymatic activity for six months and can be used repeatedly.