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[Synthesis and Quaternation of Pyridine-aldoxim Alkylethers (author's transl)]
Arzneimittel-Forschung
|January 1, 1976
Abstract:
Using known procedures, alkylethers of pyridine-aldoxime not described as yet were prepared and transformed into pyridinium salts. The application of a solution of a,a'-di-iodo-dimethyl-ether proved especially useful in the synthesis of bisquarternary salts with formaldehyde-acetal bridge. All the new substances are ineffective in a paraoxon poisoning. On the other hand, some salts show protective action in soman intoxication.