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Updated: Aug 8, 2026

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians
Published on: May 12, 2019
[Reproduction-toxicologic tests with a new beta-mimetic agent clenbuterol (NAB 365) (AUTHOR'S TRANSL)]
Abstract:
The reproduction-toxicologic tests on rat and rabbit yielded no indication of a teratogenic potency of the beta-mimetic agent 4-amino-alpha-[(tert.-butylamino)methyl]-3,5-dichlorobenzyl alcohol-hydrochloride (clenbuterol, NAB 365). The fertility test showed no signs of reduced fertility. Excessive dosage of NAB 365 to pregnant rats led to an increased mortality of the pups during the neonatal period. A dosage of 1 mg/kg is regarded as the maximum tolerated dosage in perinatal toxicity tests.
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