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Detection of bile duct cancer by autofluorescence cholangioscopy: a pilot study
1Department of Surgery, National Cancer Center Hospital East, Chiba, Japan.
Background/Aims:
There is increasing interest in the detection of malignancy by autofluorescence endoscopy. This is the first report on autofluorescence endoscopy in bile duct cancer.
Methodology:
Nine patients with bile duct cancer underwent percutaneous transhepatic autofluorescence cholangioscopy using light-induced fluorescence endoscopy in the gastrointestinal tract (LIFE-GI) system.
Results:
The cancerous lesion had quite a different color in comparison with normal mucosa, which was seen as light blue, by the autofluorescence endoscopy. In all patients, cancerous legions were observed as dark red. Additionally, in 7 of the 9 cases a white fluorescence was also seen in the cancerous lesion.
Conclusions:
In previous reports on the gastrointestinal tract and bronchial tree, cancerous lesions appeared dark red when examined by autofluorescence endoscopy. In our study, it is suggested that a white fluorescence is also an important finding for making diagnosis of bile duct cancer by the autofluorescence endoscopy.