Related Experiment Videos
Ibuprofen treatment versus gradual introduction of interferon beta-1b in patients with MS
G P Rice1, G C Ebers, F D Lublin
1London Health Sciences Centre, Ontario, Canada.
Neurology
|June 17, 1999
Abstract:
Flu-like symptoms and injection site reactions are adverse effects of treatment with interferon beta-1b in patients with MS. We compared gradual dose escalation, ibuprofen treatment, or their combination in an open-label study. The combination reduced the incidence of flu-like symptoms to rates comparable with the placebo group in the pivotal trial but increased the frequency of injection site reactions, albeit modestly and transiently.