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Related Concept Videos

Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...

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Related Experiment Video

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New Variations for Strategy Set-shifting in the Rat
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Use of laboratory animals

M Hauswald

    Lancet (London, England)
    |June 17, 1999
    PubMed
    Summary

    No abstract available in PubMed .

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