Related Experiment Video
Updated: Sep 30, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
Published on: December 18, 2016
[Fronto-temporal degenerative dementia. A modern neuropathologic approach]
J J Hauw1, C Duyckaerts, D Seilhean
1Laboratoire de Neuropathologie R. Escourolle, Université Pierre et Marie Curie (Paris VI), INSERM U 360, Association Claude Bernard, Hôpital de la Salpêtrière, Paris.
Abstract:
The classification of degenerative dementias with fronto-temporal atrophy has been debated since the description of Pick's disease. The study of a clinico-pathological series of 10 cases using immunohistochemistry lead to the following conclusions: reserving the name of Pick's disease to those cases with argyrophilic inclusions, the most recognisable and characteristic marker at neuropathological examination, allows an easy and reliable diagnosis; keeping on with the splitting of these disorders into various clinico-pathologic entities seems today more useful than grouping them into a single syndrome until new data, based for example on genetic analysis, show that different phenotypes correspond to the same disease.
Related Concept Videos
Parkinson's Disease: Overview
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Alzheimer's Disease: Treatment
Dementia
The progression of dementia is generally gradual.
Alzheimer Disease ll: Pathophysiology
Dementia l: Introduction

