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Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
Published on: June 14, 2016
[Ischemic cardiopathy in the hypertensive]
1Serviço de Cardiologia do Hospital Militar Principal, Lisboa.
Insights
Arterial hypertension and coronary heart disease (CHD) share common risk factors and remodeling processes, often co-existing in patients. Managing hypertension involves assessing total CHD risk and modifying lifestyle for better cardiovascular health.
Area of Science:
- Cardiovascular Medicine
- Hypertension Research
- Coronary Heart Disease Etiology
Context:
- Arterial hypertension and coronary heart disease (CHD) represent clinical manifestations of cardiovascular remodeling.
- These conditions result from complex interactions of biological, psychological, social, and individual metabolic factors.
- The simultaneous presence of hypertension and CHD in patients is common due to shared underlying mechanisms.
Purpose:
- To highlight the interconnectedness of arterial hypertension and coronary heart disease (CHD).
- To emphasize the importance of assessing total CHD risk in hypertensive individuals.
- To underscore the need for comprehensive lifestyle modification strategies.
Summary:
- Cardiovascular remodeling underlies both arterial hypertension and coronary heart disease (CHD).
- Shared risk factors and similar remodeling processes contribute to the frequent co-occurrence of these conditions.
- Effective management requires a holistic approach, addressing blood pressure and overall CHD risk burden.
Impact:
- Informs clinical practice regarding comprehensive risk assessment in hypertensive patients.
- Promotes integrated management strategies for cardiovascular diseases.
- Enhances understanding of the multifactorial nature of cardiovascular remodeling and disease progression.
Abstract:
Arterial hypertension and coronary heart disease (CHD) are the clinical expression of cardiovascular remodelling, the altered cell population of the cardiovascular system being the result from many biological, psychological and social factors and genetic, enzymatic, humoral and metabolic dysfunction of the individual subject. Both diseases are affected by many common factors and have some similar aspects of the remodeling process, and these are reasons for their simultaneous presence in many patients. The assessment of the total burden of CHD risk in the hypertensive patient and the strategy to modify lifestyle and reduce not only the blood pressure, but also the total burden of risk, is therefore important.
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