Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Recent progress in akathisia].

J Horiguchi1, H Yamashita, Y Kuramoto

  • 1Department of Psychiatry and Neurosciences, Hiroshima University School of Medicine, Japan.

Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology
|June 22, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuroprotective mechanism of bromocriptine.

Lancet (London, England)·1995
Same author

Serum 7 alpha-hydroxycholesterol as a new parameter of liver function in patients with chronic liver diseases.

Hepatology (Baltimore, Md.)·1995
Same author

Recurrent cervical abscess due to piriform sinus fistula.

The Journal of laryngology and otology·1995
Same author

Force-velocity relations of rat cardiac myosin isozymes sliding on algal cell actin cables in vitro.

Biochimica et biophysica acta·1995
Same author

Cloning and characterization of a human type II receptor for bone morphogenetic proteins.

Proceedings of the National Academy of Sciences of the United States of America·1995
Same author

Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma.

International journal of cancer·1995

Neuroleptic-induced akathisia requires precise diagnosis across acute, tardive, withdrawal, and chronic forms. Understanding its dopamine receptor inhibition and potential risk factors like iron deficiency is key for effective management.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Psychiatry

Context:

  • Neuroleptic-induced akathisia (NIA) is a common and distressing side effect of antipsychotic medications.
  • Accurate diagnosis is crucial for appropriate management and patient well-being.

Purpose:

  • To delineate the diagnostic criteria for different types of neuroleptic-induced akathisia.
  • To explore the underlying pharmacological and pathophysiological mechanisms of NIA.
  • To identify potential risk factors and associated neurological conditions.

Summary:

  • NIA presents in acute, tardive, withdrawal, and chronic forms, necessitating diagnosis through subjective reports and objective findings.
  • Key diagnostic tools include instrumental methods and rating scales.
  • Pharmacologically, NIA involves dopamine receptor inhibition, potentially linked to GABAergic, noradrenergic, and serotonergic dysfunction.

Related Experiment Videos

  • Risk factors include iron deficiency and hyperglycemia, while thalamic lesions can mimic drug-induced akathisia.

    • Impact:

    • Highlights the importance of differentiating NIA subtypes for tailored treatment strategies.
    • Emphasizes avoiding long-term use of anticholinergics and benzodiazepines in managing NIA.
    • Provides a comprehensive overview for clinicians on diagnosing and understanding NIA.