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[Observation on oligodendroglioma with light, electron microscopy and immunohistochemistry]
Abstract
Objective:
To investigate the ultrastructural and histological characteristics of oligodendroglioma (ODG).
Methods:
By means of light microscopy and partially electron microscopy and immunohistochemistry, 65 cases of ODG were observed.
Results:
According to WHO classification of the tumor, all 65 cases of ODG were graded in the degree of differentiation of tumor cells, showing 19 cases of Grade I, 32 cases of Grade II and 14 cases of Grade III.
Conclusions:
(1) The presence of glial filaments in tumor cells may be explained as a heterogeneity in differentiation. (2) Besides the degree of differentiation, some other criteria such as cellular density and mitotic activity are also closely related to the grading of ODG.