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Published on: August 25, 2014
Longitudinal study of behaviour disorders in low birthweight infants
C J Stevenson1, P Blackburn, P O Pharoah
1Foundation for the Study of Infant Deaths Unit of Perinatal and Paediatric Epidemiology Department of Public Health University of Liverpool Liverpool L69 3GB, UK.
Insights
Low birthweight infants show higher rates of behavioral issues. However, due to their small numbers, the overall population risk for behavioral disorders remains low at 2-3%.
Area of Science:
- Developmental Pediatrics
- Child Psychology
- Public Health
Background:
- Low birthweight is a known risk factor for developmental and behavioral challenges.
- Understanding the long-term behavioral outcomes in low birthweight survivors is crucial for early intervention and support.
Purpose of the Study:
- To compare the prevalence of childhood and adolescent behavioral problems in low birthweight infants versus matched controls.
- To assess the longitudinal changes in behavioral problems from age 8 to 14 years.
Main Methods:
- A cohort study design was employed, including survivors of birthweight ≤1500 g born in 1980-1981 and matched controls.
- Rutter questionnaires were administered to parents and teachers at ages 8 and 14 years.
- Children with pre-existing clinical disabilities were excluded from the analysis.
Main Results:
- At age 14, both parent and teacher reports indicated a higher prevalence of behavioral problems in the low birthweight group compared to controls.
- Concordant parent and teacher reports identified pervasive behavioral problems in 9% of cases versus 3% of controls.
- Longitudinal analysis showed a decrease in behavioral problems from age 8 to 14 based on parental reports, but not teacher reports.
Conclusions:
- Low birthweight infants are at an elevated risk for behavioral problems.
- Despite individual risk, the population attributable risk for behavioral disorders in this group is modest (2-3%) due to their small proportion of total births.
Aim:
To compare the prevalence of childhood and adolescent behavioural problems in low birthweight infants with matched controls.
Methods:
A cohort study of a geographically defined population of survivors of =1500 g birthweight born in 1980 and 1981 and age, sex, and school matched controls was undertaken. Children with a clinical disability were excluded. Data from Rutter questionnaires, completed by parents and teachers when the children were aged 8 and again at age 14 years, were assessed.
Results:
From an initial 40 321 births in 1980-81 there were 399 of birthweight =1500 g, of whom 219 survived to age 8. After exclusion of the 42 children with clinical disability, 177 cases comprised the sample. Of these, 10 (6%) refused or could not be contacted, leaving 167 cases for each of whom a matched control was obtained. At age 14 years, both parent and teacher questionnaires showed an increased prevalence of behavioural problems in cases compared with controls. The presence of a pervasive behavioural problem, when the responses of parents and teachers were concordant, was present in 9% of cases and 3% of controls. There were 132 pairs where the cases and controls were the same at ages 8 and 14 years and provided longitudinal data. The parental questionnaire showed there was a significant decrease in the prevalence of behavioural problems for cases and controls between the ages of 8 and 14 years. There was almost no longitudinal change in the prevalence of behavioural problems as shown by the teacher questionnaires.
Conclusion:
Although low birthweight infants are at increased risk of behavioural problems, because they comprise only a small proportion of all births, their population attributable risk for behavioural disorder is around 2-3%.
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