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Change in optic disc topography associated with diurnal variation in intraocular pressure
B L Lee1, L Zangwill, R N Weinreb
1Glaucoma Center and Research Laboratory, University of California at San Diego, La Jolla 92093-0946, USA.
Purpose:
A case demonstrating significant changes in optic disc topography from variation in intraocular pressure (IOP) is demonstrated.
Methods:
Within a single 24-hour period, confocal scanning laser ophthalmoscopic images were obtained in the left eye of a patient during an IOP peak (60 mmHg) and during an IOP trough (18 mmHg).
Results:
During an IOP trough, paired t tests showed significant reduction in cup area, cup volume, mean cup depth, and maximum cup depth, and a significant increase in rim area and cup-to-disc (CD) ratio.
Conclusion:
Under certain conditions, optic disc topography may be affected by diurnal variations in IOP.