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Cerebrovascular changes in neurofibromatosis.
Developmental Medicine and Child Neurology
|December 1, 1978
Summary
Neurofibromatosis can affect brain blood vessels, causing blockages in children. Pediatricians should consider cerebral vascular disease in neurofibromatosis patients with sudden neurological symptoms.
Area of Science:
- Neurology
- Pediatrics
- Vascular Medicine
Background:
- Neurofibromatosis is a genetic disorder with varied clinical manifestations.
- Vascular abnormalities are recognized complications, often involving renal arteries.
Observation:
- This study reports two pediatric cases of neurofibromatosis presenting with cerebral vascular occlusive changes.
- Cerebral angiography confirmed the vascular occlusions in both patients.
Findings:
- The findings highlight a less commonly recognized association between neurofibromatosis and cerebrovascular disease in children.
- Cerebral angiography is crucial for diagnosing these vascular complications.
Implications:
- Sudden neurological deficits in children with neurofibromatosis warrant prompt evaluation for cerebral vascular disease.
- Early recognition and management of cerebrovascular complications can improve patient outcomes.