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[Insulin and insulin therapy].

G Sindelka1

  • 1III. interní klinika 1. LF UK a VFN, Praha.

Casopis Lekaru Ceskych
|June 22, 1999
PubMed
Summary

This review covers insulin's formation, secretion, and receptor binding, detailing its therapeutic uses beyond diabetes and its historical development. It emphasizes modern insulin preparations, delivery methods, and factors influencing insulin absorption.

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Area of Science:

  • Endocrinology
  • Pharmacology

Context:

  • Insulin is a critical hormone for glucose regulation.
  • Understanding insulin's mechanisms is vital for effective therapeutic strategies.

Purpose:

  • To provide a comprehensive overview of insulin, from its discovery to current therapeutic applications.
  • To detail the history, modern preparations, and administration of insulin.
  • To explore factors influencing insulin absorption and action.

Summary:

  • The paper reviews insulin synthesis, secretion, receptor interactions, and post-receptor events.
  • It discusses indications for insulin therapy, including non-diabetology applications.
  • Key aspects covered include the evolution of insulin treatments (injections, pumps), contemporary insulin products, and influencing factors like injection site and concentration on insulin absorption.

Impact:

  • This overview serves as a valuable resource for clinicians and researchers in endocrinology and related fields.
  • It highlights the advancements in insulin therapy and the importance of optimizing insulin absorption for patient outcomes.

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