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Related Experiment Videos

An embolization containment device.

S N Oesterle1, M Hayase, D S Baim

  • 1Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA. oesterle.stephen@mgh.harvard.edu

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|June 22, 1999
PubMed
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A novel catheter system effectively traps and removes emboli during cardiovascular interventions. This GuardWire system prevents distal embolization, ensuring procedural safety in complex coronary anatomy.

Area of Science:

  • Cardiovascular Interventions
  • Medical Device Technology
  • Embolism Prevention

Background:

  • Distal embolization is a significant risk during percutaneous coronary interventions.
  • Existing embolic protection devices have limitations in complex anatomies.

Purpose of the Study:

  • To describe and evaluate a novel coaxial catheter system for distal embolization containment.
  • To assess the feasibility and safety of the PercuSurge GuardWire system in animal models.

Main Methods:

  • A 0.014" hypotube with a distal occlusion balloon (PercuSurge GuardWire) was used as a guidewire.
  • Distal emboli were trapped, and particulate debris was aspirated using an Export catheter before balloon deflation.
  • The system's deliverability and safety were assessed in tortuous coronary arteries in an animal study.

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Main Results:

  • The GuardWire system successfully trapped distal embolization during simulated interventions.
  • The system demonstrated easy delivery through complex coronary anatomy.
  • The GuardWire served as a reliable rail for delivering angioplasty balloons and stents.
  • No deep wall damage was observed from low-pressure balloon inflation.

Conclusions:

  • The PercuSurge GuardWire system is a feasible and safe embolic protection device.
  • This technology effectively contains and allows for removal of distal emboli.
  • The system facilitates complex percutaneous coronary interventions by providing embolic protection.