Vascular transformation of sinuses in bilateral cervical lymph nodes
Related Experiment Video
Updated: Oct 9, 2026

Modified Radical Neck Dissection for Cervical Metastasis
Published on: February 20, 2026
1Department of Oral Surgery, Saitama Medical Center, Saitama Medical School, Kawagoe, Japan.
Background:
Vascular transformation of sinuses (VTS) in lymph node has been infrequently reported. We present a case of incidental VTS in bilateral cervical nodes discovered at the time of operation for tongue cancer.
Methods:
Standard histopathologic review was undertaken.
Results:
In this case, a spectrum of varied vasoformative patterns involving lymph nodes in either a pan-nodal or localized fashion were identified. The hilum was occupied by smooth muscle proliferation and adipose tissue. Two nodes also displayed similar features of angiolipomatous hamartoma. No metastatic carcinoma was found in lymph nodes with VTS.
Conclusions:
This case suggests that lymphovenous congestion and distention represented the major cause through which VTS developed.
More Related Videos
Related Concept Videos
Veins of Head and Neck
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Lymphatic Vessels and Lymph Transport
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular spaces.
Detailed Structure and Function of Lymph Nodes
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
Development of the Lymphatic System
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...

