[Myelopeptides as a new group of regulatory peptides]

The paper summarizes the data available on the structural and functional characteristics of the brain marrow immunoregulatory peptides myelopeptides (MPs). It describes the amino acid sequences of 6 individual MPs, their biological properties and mechanism. MP-1 is a hexapeptide having an immunocorrective effect. MP-2 has antitumor action, MP-3 stimulates the phagocytic activity of macrophages, M-4 is a new differentiating factor. The endogenous origin of the MPs isolated, their structure, and the pattern of their biological effects lead to the conclusion that MPs represent a new group of regulatory peptides that are promising for clinical application.