Related Experiment Video
Updated: Jul 28, 2026

14:40
Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice
Published on: October 27, 2020
Anxiety and neurological disorders.
1Department of Psychiatry, University of California, Davis, Sacramento, CA 95817, USA.
Summary
Anxiety disorders are common in patients with neurologic conditions but often overlooked. This review addresses diagnostic challenges and treatment for anxiety in neurological patients.
Area of Science:
- Neurology
- Psychiatry
- Clinical Psychology
Background:
- Anxiety disorders are highly prevalent in patients with neurologic disorders, often exceeding mood disorders.
- Despite their frequency, anxiety disorders in neurologic conditions have been understudied.
- Diagnostic criteria in the Diagnostic and Statistical Manual (DSM)-III-R and DSM-IV have contributed to this neglect.
Purpose of the Study:
- To highlight the diagnostic challenges of anxiety disorders in patients with neurologic conditions.
- To review the existing literature on the relationship between anxiety and neurologic disorders.
- To discuss differential diagnosis and treatment options for anxiety in neurologic populations.
Main Methods:
- Literature review of studies examining anxiety disorders in patients with neurologic conditions.
- Analysis of diagnostic criteria (DSM-III-R, DSM-IV) and their impact.
- Discussion of clinical presentation, differential diagnosis, and therapeutic strategies.
Main Results:
- Anxiety disorders are frequently comorbid with neurologic disorders.
- Diagnostic hierarchies and exclusion criteria in DSM versions have hindered accurate diagnosis.
- There is a need for improved diagnostic approaches and targeted treatments.
Conclusions:
- Accurate diagnosis and treatment of anxiety disorders in neurologic patients are crucial.
- Clinical guidelines should be revised to better accommodate these patients.
- Further research is needed to understand the neurobiological underpinnings and optimize interventions.
Related Concept Videos
Disorders of the Nervous Tissue
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Anxiety: Overview
Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Stress and Mental Health
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
Panic Disorder
Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
Social Anxiety Disorder
Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.

