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Efficacy of adhesive interactions in pig-to-human xenotransplantation
A R Simon1, A N Warrens, M Sykes
1Bone Marrow Transplantation Section, Transplantation Biology Research Center, Surgical Service, Massachusetts General Hospital/Harvard Medical School, MGH East, Building 149-5102, 13th Street, Boston, MA 02129, USA. asimon@artificial-organs.de
Immunology Today
|June 24, 1999
Abstract:
Successful xenotransplantation depends on many factors, one being the interactions of cross-species adhesion molecule-ligand pairs. Depending on the approach used to facilitate xenotransplantation, these interactions can play differing roles. Here, André Simon, Anthony Warrens and Megan Sykes review the existing information on pig-to-human adhesive interactions and its implication for different approaches to pig-to-human xenotransplantation.